GLP-1 receptor agonist
Liraglutide
Sold as Saxenda, Victoza — once daily, subcutaneous injection.
Mean weight change · SCALE
-8%
Placebo arm
-2.6%
Duration
56 wk
What the number means
Mean change in body weight at 56 weeks on 3.0 mg daily, in adults with overweight or obesity.
Trial averages are not a forecast for any individual. Response varies widely, the trial population was screened and supported in ways a subscription is not, and the figure describes people who stayed on the medication for the full period.
Worth knowing
- A daily injection rather than weekly, which is the main reason people leave it.
- Now available as a generic in several markets, which makes it by far the cheapest way into this class.
- Smaller average effect, but a longer real-world safety record than the newer agents.
Approved for
Type 2 diabetes (Victoza) and chronic weight management (Saxenda), with a paediatric indication from age 12 for Saxenda.